Straightforward and Expeditious One-Pot Tandem Synthesis of 3,5-Diaryl-1,2,4-Selenadiazoles from Aryl Nitriles
by Majnooni, Sahar; Almansaf, Zainab; Tsuji, Miu; Khosropoura, Ahmad R.; Zali-Boeini, Hassan; Beyzavi, M. Hassan
A one-pot process for the efficient synthesis of 3,5-diaryl-1,2,4-selenadiazoles from aryl nitriles has been developed. This tandem transformation was performed in excellent yields (91-98%) via in situ selenoamidation and a subsequent oxidative dimerization reaction. This method features relatively mild reaction conditions, operational simplicity, straightforward separation of the products, and the utilization of inexpensive reagents.
- Journal
- Synthesis (Stuttgart)
- Volume
- 51
- Issue
- 22
- Year
- 2019
- Start Page
- 4279
- ISBN/ISSN
- 0039-7881
- DOI
- 10.1055/s-0039-1690126