Margaret Myers was born on January 14, 1937. She lived and grew up in Northwest Arkansas and graduated from Fayetteville High School in Fayetteville, Arkansas in 1955. Upon graduating from high school, she attended the University of Arkansas at Fayetteville. She was a member of Alpha Lambda Delta and Sigma Alpha Iota fraternities. She received the BSE and MED degrees from the University of Arkansas where she was a member of the symphony and string quartet. Myers played the viola and during the summer of 1961 she attended the String Institute at Eastman School of Music in Rochester, New York.

During a state tour with the University of Arkansas String Ensemble, Myers visited El Dorado, Union County, Arkansas. She would later become a music teacher at Southside School in El Dorado. She was also a private teacher of piano and strings. In addition to her performances with the South Arkansas Symphony, Myers also performed with a number of other orchestras including the Twin City Symphony of Monroe, Louisiana, the Marshal (Texas) Symphony, the Henderson State Teachers College Orchestra, and the Youth Concert Orchestra of Little Rock. Myers remained an admirer of orchestral music until her death on August 27, 2005 in Kansas.