Biocompatible scaffold for sensing proteins

by Tian, Z. Ryan

This invention related to a biocompatible scaffold that can detect redox-active chemicals and biomolecules electrochemically. In one embodiment, the biocompatible scaffold includes a substrate, and a conductive layer of TiO2-containing nanowires or nano fibers formed on the substrate, wherein the conductive layer of TiO2-containing nanowires or nanofibers is formed with a pore structure, and wherein when the biocompatible scaffold is in contact with a biological analyte, one or more proteins of the biological analyte are immobilized on a surface of the conductive layer Of TiO2- containing nanowires or nanofibers so as to generate a measurable faradic current signal.

Publication Year
2012
URL
http://scholarworks.uark.edu/pat/299