Delivery of therapeutic agents by a collagen binding protein
by Ponnapakkam, Tulasi; Philominathan, Sagaya Theresa Leena; Sakon, Joshua; Katikaneni, Ranjitha; Koide, Takaki; Matsushita, Osamu; Gensure, Robert C.
Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
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