Synthesis of Bifunctional Hydroxamic Acids as Novel Ligands for the Hydrophilic Stabilization of Iron Oxide Nanoparticles

by Hofmann, Andreas; Graf, Christina; Kung, Shih-Hao; Kim, Myeongseob; Peng, Xiaogang; El-Aama, Randa; Ruehl, Eckart

A general method for synthesizing bifunctional hydroxamic acids containing carboxylic acid or amino functionalities is reported. Various products from simple alkyl to complex dendrimer-like structures are described. Such molecules have recently been used in ligand-exchange reactions for the hydrophilic stabilization of originally oleic acid protected iron oxide nanoparticles.

Journal
Synthesis (Stuttgart)
Issue
7
Year
2010
Start Page
1150
ISBN/ISSN
1437-210X; 0039-7881
DOI
10.1055/s-0029-1218654