Straightforward and Expeditious One-Pot Tandem Synthesis of 3,5-Diaryl-1,2,4-Selenadiazoles from Aryl Nitriles

by Majnooni, S.; Almansaf, Z.; Tsuji, M.; Khosropoura, A. R.; Zali-Boeini, H.; Beyzavi, M. H.

A one-pot process for the efficient synthesis of 3,5-diaryl-1,2,4-selenadiazoles from aryl nitriles has been developed. This tandem transformation was performed in excellent yields (91-98%) via in situ selenoamidation and a subsequent oxidative dimerization reaction. This method features relatively mild reaction conditions, operational simplicity, straightforward separation of the products, and the utilization of inexpensive reagents.

Journal
Synthesis-Stuttgart
Volume
51
Issue
22
Year
2019
Start Page
4279-4283
URL
https://dx.doi.org/10.1055/s-0039-1690126
ISBN/ISSN
1437-210X; 0039-7881
DOI
10.1055/s-0039-1690126