Structural studies of {Li-6} 2-lithiopyrrolidines using NMR spectroscopy
by Gawley, R. E.; Klein, R.; Ashweek, N. J.; Coldham, I.
A selection of N-substituted 2-lithiopyrrolidines were prepared and their structures were investigated by Li-6 and C-13 NMR spectroscopy. Evidence is presented for aggregation and dynamic solvation effects, depending on the nature of the N-substituent and substituents on the pyrrolidine ring. Studies were performed with N-Boc (coordinating carbonyl group), N-methoxyethyl (coordinating methoxy group) and N-alkyl (no coordinating group) heterocycles to represent three different classes of organolithiums: dipole-stabilized, unstabilized and chelated, and unstabilized.
- Journal
- Tetrahedron
- Volume
- 61
- Issue
- 13
- Year
- 2005
- Start Page
- 3271-3280
- URL
- https://dx.doi.org/10.1016/j.tet.2005.01.098
- ISBN/ISSN
- 1464-5416; 0040-4020
- DOI
- 10.1016/j.tet.2005.01.098