Selective detection of saxitoxin over tetrodotoxin using acridinylmethyl crown ether chemosensor

by Gawley, R. E.; Shanmugasundaram, M.; Thorne, J. B.; Tarkka, R. M.

At pH 7.1, saxitoxin decomposes to produce a trace impurity that can interfere with fluorescence sensing when using irradiation wavelengths near 325 nm. The fluorophore acridine is found to be a suitable component of arylmethyl crown ether chemosensors for the fluorescent detection of saxitoxin. These sensors are selective for the detection of saxitoxin over tetrodotoxin.

Journal
Toxicon
Volume
45
Issue
6
Year
2005
Start Page
783-787
URL
https://dx.doi.org/10.1016/j.toxicon.2005.01.019
ISBN/ISSN
1879-3150; 0041-0101
DOI
10.1016/j.toxicon.2005.01.019