Engineered FGF1 and FGF2 compositions and methods of use thereof
by Thallapuranam, Suresh Kumar; Agrawal, Shilpi; Gundampati, Ravi Kumar; Jayanthi, Srinivas; Wang, Tengjiao; Jones, Jake; Kolenc, Olivia; Lam, Ngoc Thien; Niyonshuti, Isabelle; Balachandran, Kartik; Quinn, Kyle; Chen, Jingyi
Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.
- Patent Number
- USUS2019284252 A1 2019-09-19
- Application Number
- B2
- Publication Year
- 2022
- URL
- https://scholarworks.uark.edu/pat/433