Delivery of therapeutic agents by a collagen binding protein
by Ponnapakkam, Tulasi; Philominathan, Sagaya Theresa Leena; Sakon, Joshua; Katikaneni, Ranjitha; Koide, Takaki; Matsushita, Osamu; Gensure, Robert C.
Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
- Patent Number
- USUS2015038423 A1 2015-02-05
- Application Number
- B2
- Publication Year
- 2016
- URL
- https://scholarworks.uark.edu/pat/335