An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity
by Xia, X. H.; Yang, M. X.; Oetjen, L. K.; Zhang, Y.; Li, Q. G.; Chen, J. Y.; Xia, Y. N.
A gold nanocage and dye conjugate has been demonstrated for use with photoacoustic imaging and fluorescence detection of protease activity. The detection sensitivity could be maximized by using gold nanocages with a localized surface plasmon resonance peak away from the emission peak of the dye. These hybrids can be potentially used as multimodal contrast agents for molecular imaging.
- Journal
- Nanoscale
- Volume
- 3
- Issue
- 3
- Year
- 2011
- Start Page
- 950-953
- URL
- https://dx.doi.org/10.1039/c0nr00874e
- ISBN/ISSN
- 2040-3372; 2040-3364
- DOI
- 10.1039/c0nr00874e