Electron-Transfer from Cytochrome B(5) to Cytochrome-C

by Durham, Bill; Fairris, Jill L.; McLean, Mark; Millett, Francis Spencer; Scott, Jill R.; Sligar, Stephen G.; Willie, Anne N.

The reaction of cytochrome b(5) with cytochrome c has become a very prominent system for investigating fundamental questions regarding interprotein electron transfer. One of the first computer modeling studies of electron transfer and protein/protein interaction was reported using this system. Subsequently, numerous studies focused on the experimental determination of the features which control protein/protein interactions. Kinetic measurements of the intracomplex electron transfer reaction have only appeared in the last 10 years. The current review will provide a summary of the kinetic measurements and a critical assessment of the interpretation of these experiments.

Journal
Journal of Bioenergetics and Biomembranes
Volume
27
Issue
3
Year
1995
Start Page
331
ISBN/ISSN
1573-6881; 0145-479X
DOI
10.1007/BF02110102