Unprecedented alkene stereocontrol in the Claisen rearrangement of cyclic bis-allylic esters
by McFarland, Christopher Michael; Hutchison, John Michael; McIntosh, Matt C.
[GRAPHICS] The Ireland and ester enolate Claisen rearrangements of tertiary substituted bis-allylic esters derived from cyclohexenones afford pentenoic acids that possess tri- and tetrasubstituted alkylidenes with unprecedented levels of stereoselectivity. In some cases the higher energy exocyclic alkene is the major product.
- Organic Letters
- Start Page
- 1523-7052; 1523-7060