Microfabricated recessed disk microelectrodes: characterization in static and convective solutions
by Fritsch, Ingrid; Henry, Charles Sherman; Bowen, Benjamin P.; Vandaveer, Walter R.; Bratcher, Nicole
The present invention relates to microfabricated recessed disk microelectrodes. More specifically, this invention relates to microcavities containing microelectrodes and being separated from surrounding media by a lipid bilayer that is anchored to the rim of the microcavity. The invention also relates to microcavities having a hole in the bottom in order to relieve osmotic pressure. The invention also relates to arrays of such microcavities. Construction and characterization of microfabricated recessed disk microelectrodes (RDMs) of 14 and 55 µm diameter are reported. Hybrid blamers were constructed by fusion of vesicles of dimyristoylphosphatidyl choline (DMPC), which forms the top layer, with EtOH-rinsed SAMs of hexadecanethiol on Au, which form the bottom layer. Gramicidin A was included in the modifying solutions to incorporate it into hybrid blamers.
- Patent Number
- USUS2003015422 A1 2003-01-23
- Application Number
- B2
- Publication Year
- 2007
- URL
- https://scholarworks.uark.edu/pat/106