SV119-gold nanocage conjugates: a new platform for targeting cancer cells via sigma-2 receptors

by Wang, Yucai; Xu, Jinbin; Xia, Xiaohu; Yang, Miaoxin; Vangveravong, Suwanna; Chen, Jingyi; Mach, Robert H.; Xia, Younan

We have functionalized the surface of gold nanocages with SV119, a synthetic small molecule specific to sigma-2 receptors, and then demonstrated the capability of this new class of conjugates for targeting cancer cells.