Enzymichromism - Determination of the Dielectric-Properties of an Enzyme Active-Site
by Kanski, Ryszard; Murray, Christopher James
The negative solvatochromic and enzymichromic properties of 4-carbamidopyridinium cyclopentadienylide, 3, are presented. Tle 78 nm bathochromic shift of the long wavelength absorption band of 3 upon going from water to the horse liver alcohol dehydrogenase (HLADH)-NADH ternary complex is consistent with a low dielectric for the hydrophobic binding pocket of this enzyme.
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- 1873-3581; 0040-4039