An introduction to MALDI-TOF MS

by Liyanage, Rohana; Lay, Jackson O., Jr.

A review. A new method for bacterial taxonomy is described. The new approach developed for such anal. is an ionization method, specifically known as matrix-assisted laser desorption ionization. This new method matrix-assisted laser desorption ionization-coupled with time-of-flight (TOF) mass spectrometry can also be applied to anal. of proteins and peptides. The anal. with such compds. can be done directly from the whole cells, avoiding any sepn., fractionation or clean-up, making the method very efficient and rapid.