Evidence of Xenon Transport through the Gramicidin Channel - a Xe-129-Nmr Study
by McKim, S.; Hinton, J. F.
Evidence is presented for Xe transport through the gramicidin A channel. This evidence for Xe transport through gramicidin A channels has been obtained using Xe-129-NMR spectroscopy. Three experiments were utilized. The first experiment involved monitoring the change in the chemical shift of Xe-129 in the presence of increasing gramicidin A concentration, the second observed the effect on the Xe-129 chemical shift with gramicidin A channels photochemically altered by UV light and the third determined the effect of gramicidin A channels blocked by Ba2+ on the Xe-129 chemical shift. The results of these three experiments indicate that Xe transports through the gramicidin A channel.
- Journal
- Biochimica et Biophysica Acta-Biomembranes
- Volume
- 1193
- Issue
- 1
- Year
- 1994
- Start Page
- 186-198
- URL
- https://dx.doi.org/10.1016/0005-2736(94)90348-4
- ISBN/ISSN
- 0005-2736
- DOI
- 10.1016/0005-2736(94)90348-4