Are biosensor arrays in one membrane possible? A combination of multifrequency impedance measurements and chemometrics

by Lindholm-Sethson, Britta; Nyström, Josefina; Geladi, Paul; Koeppe II, R. Erdman; Nelson, Andrew; Whitehouse, Conor

A novel concept of a membrane-based micro-array biosensor is presented. The methodology is based on a single lipid membrane interrogated with electrochemical impedance techniques followed by multivariate data analysis. A single membrane is designed so that relaxation processes with a range of time constants can be probed at different potentials. A range of other approaches cited in the literature is reviewed.

Journal
Analytical and Bioanalytical Chemistry
Volume
377
Issue
3
Year
2003
Start Page
478
ISBN/ISSN
1618-2650; 1618-2642
DOI
10.1007/s00216-003-2103-y