Are biosensor arrays in one membrane possible? A combination of multifrequency impedance measurements and chemometrics
by Lindholm-Sethson, Britta; Nyström, Josefina; Geladi, Paul; Koeppe II, R. Erdman; Nelson, Andrew; Whitehouse, Conor
A novel concept of a membrane-based micro-array biosensor is presented. The methodology is based on a single lipid membrane interrogated with electrochemical impedance techniques followed by multivariate data analysis. A single membrane is designed so that relaxation processes with a range of time constants can be probed at different potentials. A range of other approaches cited in the literature is reviewed.
- Journal
- Analytical and Bioanalytical Chemistry
- Volume
- 377
- Issue
- 3
- Year
- 2003
- Start Page
- 478
- ISBN/ISSN
- 1618-2650; 1618-2642
- DOI
- 10.1007/s00216-003-2103-y