Selective detection of saxitoxin over tetrodotoxin using acridinylmethyl crown ether chemosensor

by Gawley, Robert E.; Shanmugasundaram, Muthian; Thorne, John Burns; Tarkka, Richard M.

At pH 7.1, saxitoxin decomposes to produce a trace impurity that can interfere with fluorescence sensing when using irradiation wavelengths near 325 nm. The fluorophore acridine is found to be a suitable component of arylmethyl crown ether chemosensors for the fluorescent detection of saxitoxin. These sensors are selective for the detection of saxitoxin over tetrodotoxin. (c) 2005 Elsevier Ltd. All rights reserved.

Journal
Toxicon
Volume
45
Issue
6
Year
2005
Start Page
783
ISBN/ISSN
1879-3150; 0041-0101
DOI
10.1016/j.toxicon.2005.01.019