Selective detection of saxitoxin over tetrodotoxin using acridinylmethyl crown ether chemosensor
by Gawley, R. E.; Shanmugasundaram, M.; Thorne, J. B.; Tarkka, R. M.
At pH 7.1, saxitoxin decomposes to produce a trace impurity that can interfere with fluorescence sensing when using irradiation wavelengths near 325 nm. The fluorophore acridine is found to be a suitable component of arylmethyl crown ether chemosensors for the fluorescent detection of saxitoxin. These sensors are selective for the detection of saxitoxin over tetrodotoxin.