A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products. | Advanced Methods in Structural Biology | Book Section | 2023 |
Targeting K-Ras Mutations Show Promise Towards Ending Ras's "Undruggable" Era | Protein and Peptide Letters | Journal Article | 2022 |
Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion products | Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences | Journal Article | 2021 |
Biochemical and Biophysical Approaches to Characterize the Molecular Basis of Abnormal Cell Signaling Function Involving Ras-Related Proteins. | Abstracts of Papers of the American Chemical Society | Abstract | 2021 |
Novel Strategies to Tackle Ras-Related Cancer: An Opinion Based on Two Recent Reviews | American Journal of Biomedical Science and Research | Journal Article | 2020 |
Characterizing the Influence of Two Small Molecule Targets Towards the Ras-Related Protein Cdc42 | Biophysical Journal | Abstract | 2020 |
Closing the STEM Labor Gap through a Path to Graduation for Low Income, Rural Students | 2020 ASEE Virtual Annual Conference | Conference Paper | 2020 |
Work in Progress: A Path to Graduation: Helping First-Year Low Income, Rural STEM Students Succeed | 2019 ASEE Annual Conference and Exposition | Conference Paper | 2019 |
The Effects of a Small Molecule Inhibitor on Cdc42, Its Mutant and Its Interaction with Effector Proteins | Protein Science | Abstract | 2019 |
Characterizing the Direct Influence of a Small Molecule on a RAS-Related Protein Interaction | Biophysical Journal | Abstract | 2019 |
Characterizing the Direct Influence of a Small Molecule on a Ras-Related Protein Interaction | Biophysical Journal | Abstract | 2018 |
Studying the Effects of a Small Molecule Inhibitor on a Ras-Related Protein | Protein Science | Abstract | 2018 |
Trypsin as a Biochemical Tool for the Characterization of Ras-Related Protein Structure and Function | Journal of Science and Medicine (JSM): Enzymology and Protein Science | Journal Article | 2018 |
Characterization of a small molecule's influence on a Ras-related protein-protein interaction | Abstracts of Papers of the American Chemical Society | Abstract | 2018 |
Two small molecules, ZCL278 and AZA197 show promise in influencing protein interactions involving the ras-related protein cell division cycle 42 [Cdc42] to modulate its oncogenic potential | Open Journal of Biophysics | Journal Article | 2017 |
Biochemical and Biophysical Characterization of a Small Molecule Interaction with the Ras-Related Protein Cdc42 | Biophysical Journal | Abstract | 2017 |
Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor | Small GTPases | Journal Article | 2016 |
The versatility of isothermal titration calorimetry in modern biology | Journal of Analytical and Bioanalytical Techniques | Journal Article | 2015 |
NMR Spectroscopy Provides a Novel Bioanalytical and Biophysical Approach towards the Characterization of Protein Interactions Involved in the Integration of RAS Signaling | Journal of Analytical and Bioanalytical Techniques | Journal Article | 2015 |
Intrinsic GTP Hydrolysis is Observed For a Switch 1 Mutant of Cdc42 in the Presence of a Specific GTPase Inhibitor | Protein Science | Abstract | 2014 |
Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor | Biochimica et Biophysica Acta-Proteins and Proteomics | Journal Article | 2014 |
Characterization of the Interaction between Rheb and a Truncated Construct of Tuberous Sclerosis Complex 2 (TSC2) and the Potential Effect of Heparin on TSC2-Stimulated GTP Hydrolysis | Biophysical Journal | Abstract | 2013 |
Prospective development of small molecule targets to oncogenic Ras proteins | Open Journal of Biophysics | Journal Article | 2013 |
A Characterization of the Protein-Protein Interaction of the Ras Protein, Rheb, with Tuberous Sclerosis Complex 2 (TSC2), and the Effect of Heparin Mimicking Biomolecules on This Interaction | Protein Science | Abstract | 2012 |
Expression and Purification of Cdc42 and PBD46 | FASEB Journal | Abstract | 2012 |
A Switch I Mutant of Cdc42 Exhibits Less Conformational Freedom | Biochemistry | Journal Article | 2011 |
Degradation of the nucleotide GDP from the ras protein Cdc42 wild type | Abstracts of Papers of the American Chemical Society | Abstract | 2011 |
Characterization of Cdc42 and its mutant Cdc(T35A) | Abstracts of Papers of the American Chemical Society | Abstract | 2010 |
NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1) | Biochimica et Biophysica Acta-Biomembranes | Journal Article | 2010 |
A method for the prevention of thrombin-induced degradation of recombinant proteins | Analytical Biochemistry | Journal Article | 2008 |
Cdc42 Mutants Exhibit Differential Binding to PBD46 of mPAK Using Flourescence and Isothermal Titration Calorimetry | Abstracts of Papers of the American Chemical Society | Abstract | 2008 |
Expression of, and Preliminary Biophysical Characterization of a Minimal Binding Domain Peptide of TSC2 That Binds to the Small GTPase Rheb | Abstracts of Papers of the American Chemical Society | Abstract | 2008 |
An Innovative Method for the Purification of Recombinant Proteins | Abstracts of Papers of the American Chemical Society | Abstract | 2008 |
NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42 | Biomolecular NMR Assignments | Journal Article | 2007 |