CHBC Faculty Publications

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Author: Adams, Paul D.

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TitlePublication NamePub. TypeYear
A Simple Purification Method for Heat-Stable Recombinant Low Molecular Weight Proteins and Peptides Via GST-Fusion Products.Advanced Methods in Structural BiologyBook Section2023
Targeting K-Ras Mutations Show Promise Towards Ending Ras's "Undruggable" EraProtein and Peptide LettersJournal Article2022
Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion productsJournal of Chromatography B-Analytical Technologies in the Biomedical and Life SciencesJournal Article2021
Biochemical and Biophysical Approaches to Characterize the Molecular Basis of Abnormal Cell Signaling Function Involving Ras-Related Proteins.Abstracts of Papers of the American Chemical SocietyAbstract2021
Novel Strategies to Tackle Ras-Related Cancer: An Opinion Based on Two Recent ReviewsAmerican Journal of Biomedical Science and ResearchJournal Article2020
Characterizing the Influence of Two Small Molecule Targets Towards the Ras-Related Protein Cdc42Biophysical JournalAbstract2020
Closing the STEM Labor Gap through a Path to Graduation for Low Income, Rural Students2020 ASEE Virtual Annual ConferenceConference Paper2020
Work in Progress: A Path to Graduation: Helping First-Year Low Income, Rural STEM Students Succeed2019 ASEE Annual Conference and ExpositionConference Paper2019
The Effects of a Small Molecule Inhibitor on Cdc42, Its Mutant and Its Interaction with Effector ProteinsProtein ScienceAbstract2019
Characterizing the Direct Influence of a Small Molecule on a RAS-Related Protein InteractionBiophysical JournalAbstract2019
Characterizing the Direct Influence of a Small Molecule on a Ras-Related Protein InteractionBiophysical JournalAbstract2018
Studying the Effects of a Small Molecule Inhibitor on a Ras-Related ProteinProtein ScienceAbstract2018
Trypsin as a Biochemical Tool for the Characterization of Ras-Related Protein Structure and FunctionJournal of Science and Medicine (JSM): Enzymology and Protein ScienceJournal Article2018
Characterization of a small molecule's influence on a Ras-related protein-protein interactionAbstracts of Papers of the American Chemical SocietyAbstract2018
Two small molecules, ZCL278 and AZA197 show promise in influencing protein interactions involving the ras-related protein cell division cycle 42 [Cdc42] to modulate its oncogenic potentialOpen Journal of BiophysicsJournal Article2017
Biochemical and Biophysical Characterization of a Small Molecule Interaction with the Ras-Related Protein Cdc42Biophysical JournalAbstract2017
Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitorSmall GTPasesJournal Article2016
The versatility of isothermal titration calorimetry in modern biologyJournal of Analytical and Bioanalytical TechniquesJournal Article2015
NMR Spectroscopy Provides a Novel Bioanalytical and Biophysical Approach towards the Characterization of Protein Interactions Involved in the Integration of RAS SignalingJournal of Analytical and Bioanalytical TechniquesJournal Article2015
Intrinsic GTP Hydrolysis is Observed For a Switch 1 Mutant of Cdc42 in the Presence of a Specific GTPase InhibitorProtein ScienceAbstract2014
Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factorBiochimica et Biophysica Acta-Proteins and ProteomicsJournal Article2014
Characterization of the Interaction between Rheb and a Truncated Construct of Tuberous Sclerosis Complex 2 (TSC2) and the Potential Effect of Heparin on TSC2-Stimulated GTP HydrolysisBiophysical JournalAbstract2013
Prospective development of small molecule targets to oncogenic Ras proteinsOpen Journal of BiophysicsJournal Article2013
A Characterization of the Protein-Protein Interaction of the Ras Protein, Rheb, with Tuberous Sclerosis Complex 2 (TSC2), and the Effect of Heparin Mimicking Biomolecules on This InteractionProtein ScienceAbstract2012
Expression and Purification of Cdc42 and PBD46FASEB JournalAbstract2012
A Switch I Mutant of Cdc42 Exhibits Less Conformational FreedomBiochemistryJournal Article2011
Degradation of the nucleotide GDP from the ras protein Cdc42 wild typeAbstracts of Papers of the American Chemical SocietyAbstract2011
Characterization of Cdc42 and its mutant Cdc(T35A)Abstracts of Papers of the American Chemical SocietyAbstract2010
NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1)Biochimica et Biophysica Acta-BiomembranesJournal Article2010
A method for the prevention of thrombin-induced degradation of recombinant proteinsAnalytical BiochemistryJournal Article2008
Cdc42 Mutants Exhibit Differential Binding to PBD46 of mPAK Using Flourescence and Isothermal Titration CalorimetryAbstracts of Papers of the American Chemical SocietyAbstract2008
Expression of, and Preliminary Biophysical Characterization of a Minimal Binding Domain Peptide of TSC2 That Binds to the Small GTPase RhebAbstracts of Papers of the American Chemical SocietyAbstract2008
An Innovative Method for the Purification of Recombinant ProteinsAbstracts of Papers of the American Chemical SocietyAbstract2008
NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42Biomolecular NMR AssignmentsJournal Article2007