CHBC Faculty Publications

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Author: Adams, Paul D.

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TitlePublication NamePub. TypeYear
Biochemical and Biophysical Approaches to Characterize the Molecular Basis of Abnormal Cell Signaling Function Involving Ras-Related Proteins.Abstracts, 55th Midwest Regional Meeting of the American Chemical Society, Springfield, MO, United States, October 20-22, 2021Abstract2021
Simplification of the purification of heat stable recombinant low molecular weight proteins and peptides from GST-fusion productsJournal of Chromatography B-Analytical Technologies in the Biomedical and Life SciencesJournal Article2021
Closing the STEM Labor Gap through a Path to Graduation for Low Income, Rural Students2020 ASEE Virtual Annual Conference Content AccessConference Proceedings2020
Novel Strategies to Tackle Ras-Related Cancer: An Opinion Based on Two Recent ReviewsAmerican Journal of Biomedical Science and ResearchJournal Article2020
Characterizing the Influence of Two Small Molecule Targets Towards the Ras-Related Protein Cdc42Biophysical JournalAbstract2020
Work in Progress: A Path to Graduation: Helping First-Year Low Income, Rural STEM Students Succeed2019 ASEE Annual Conference and ExpositionConference Proceedings2019
Characterizing the Direct Influence of a Small Molecule on a RAS-Related Protein InteractionBiophysical JournalAbstract2019
Characterization of a small molecule's influence on a Ras-related protein-protein interactionAbstracts of Papers, 255th ACS National Meeting and Exposition, New Orleans, LA, United States, March 18-22, 2018Abstract2018
Characterizing the Direct Influence of a Small Molecule on a Ras-Related Protein InteractionBiophysical JournalAbstract2018
Trypsin as a Biochemical Tool for the Characterization of Ras-Related Protein Structure and FunctionJournal of Science and Medicine (JSM): Enzymology and Protein ScienceJournal Article2018
Biochemical and Biophysical Characterization of a Small Molecule Interaction with the Ras-Related Protein Cdc42Biophysical JournalAbstract2017
Two Small Molecules, ZCL278 and AZA197 Show Promise in Influencing Protein Interactions Involving the Ras-Related Protein Cell division cycle 42 [Cdc42] to Modulate Its Oncogenic PotentialOpen Journal of BiophysicsJournal Article2017
Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitorSmall GTPasesJournal Article2016
NMR Spectroscopy Provides a Novel Bioanalytical and Biophysical Approach towards the Characterization of Protein Interactions Involved in the Integration of RAS SignalingJournal of Analytical and Bioanalytical TechniquesJournal Article2015
The Versatility of Isothermal Titration Calorimetry in Modern BiologyJournal of Analytical and Bioanalytical TechniquesJournal Article2015
Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factorBiochimica et Biophysica Acta-Proteins and ProteomicsJournal Article2014
Intrinsic GTP Hydrolysis is Observed For a Switch 1 Mutant of Cdc42 in the Presence of a Specific GTPase InhibitorProtein ScienceConference Proceedings2014
Characterization of the Interaction between Rheb and a Truncated Construct of Tuberous Sclerosis Complex 2 (TSC2) and the Potential Effect of Heparin on TSC2-Stimulated GTP HydrolysisBiophysical JournalAbstract2013
Prospective development of small molecule targets to oncogenic Ras proteinsOpen Journal of BiophysicsJournal Article2013
Expression and Purification of Cdc42 and PBD46FASEB JournalAbstract2012
A Characterization of the Protein-Protein Interaction of the Ras Protein, Rheb, with Tuberous Sclerosis Complex 2 (TSC2), and the Effect of Heparin Mimicking Biomolecules on This InteractionProtein ScienceConference Proceedings2012
Degradation of the nucleotide GDP from the ras protein Cdc42 wild typeAbstracts of Papers, 241st ACS National Meeting and Exposition, Anaheim, CA, United States, March 27-31, 2011Abstract2011
A Switch I Mutant of Cdc42 Exhibits Less Conformational FreedomBiochemistryJournal Article2011
Characterization of Cdc42 and its mutant Cdc(T35A)Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010Abstract2010
NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1)Biochimica et Biophysica Acta-BiomembranesJournal Article2010
An Innovative Method for the Purification of Recombinant ProteinsAbstracts, 64th Southwest Regional Meeting of the American Chemical Society, Little Rock, AR, United States, October 1-4, 2008Abstract2008
Cdc42 Mutants Exhibit Differential Binding to PBD46 of mPAK Using Flourescence and Isothermal Titration CalorimetryAbstracts, 64th Southwest Regional Meeting of the American Chemical Society, Little Rock, AR, United States, October 1-4, 2008Abstract2008
Expression of, and Preliminary Biophysical Characterization of a Minimal Binding Domain Peptide of TSC2 That Binds to the Small GTPase RhebAbstracts, 64th Southwest Regional Meeting of the American Chemical Society, Little Rock, AR, United States, October 1-4, 2008Abstract2008
A method for the prevention of thrombin-induced degradation of recombinant proteinsAnalytical BiochemistryJournal Article2008
NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42Biomolecular NMR AssignmentsJournal Article2007