CHBC Faculty Publications

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Author: Kumar, Thallapuranam Krishnaswamy Suresh

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TitlePublication NamePub. TypeYear
Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 ProteinBiophysical JournalAbstract2021Find It
Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell SignalingCurrent Drug TargetsJournal Article2021Find It
Silver Ions Caused Faster Diffusive Dynamics of Histone-Like Nucleoid-Structuring Proteins in Live BacteriaApplied and Environmental MicrobiologyJournal Article2020Find It
Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancerBiochimica et Biophysica Acta-Molecular Cell ResearchJournal Article2020Find It
Silver Ions Caused Faster Diffusion of H-NS Proteins in Live E. coli by Weakening the Binding Between H-NS Proteins and DNABiophysical JournalAbstract2020Find It
Structural Propensity in the C-terminal Domain of the ALbino3 Translocase in ThylakoidsFASEB JournalJournal Article2020Find It
Physicochemical properties of soy protein hydrolysate and its formulation and stability with encapsulated probiotic under in vitro gastrointestinal environmentJournal of Food ScienceJournal Article2020Find It
DNA aptamer-based rolling circle amplification product as a novel immunological adjuvantScientific ReportsJournal Article2020Find It
Biocompatible, Injectable Anionic Hydrogels Based on Poly(Oligo Ethylene Glycol Monoacrylate-co-Acrylic Acid) for Protein DeliveryAdvanced TherapeuticsJournal Article2019Find It
Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activityBiochemical and biophysical research communicationsJournal Article2019Find It
A Comprehensive Investigation of the Stabilization of Monomeric Hfgf1 by Heparin Hexasaccharide using Microsecond-Level MD Simulations and Enhanced Sampling TechniquesBiophysical JournalAbstract2019Find It
Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivityJournal of Biological ChemistryJournal Article2019Find It
Identification of avian vasotocin receptor subtype-specific antagonists involved in the stress response of the chicken, Gallus gallusJournal of Biomolecular Structure and DynamicsJournal Article2019Find It
NMR Methods to Characterize Protein-Ligand InteractionsNatural Product CommunicationsJournal Article2019Find It
DESIGNING FRET BASED ASSAYS TO STUDY THE BINDING OF FIBROBLAST GROWTH FACTOR TO ITS RECEPTORProtein ScienceJournal Article2019Find It
Heparin affinity tag and application thereofUS10280196Patent2019Find It
Engineered FGF compositions and methods of use thereofUS10385113Patent2019Find It
Cleavage resistant photoluminescent proteins and applications thereofUS10442842Patent2019Find It
Bioconjugation of CuInS2/ZnS quantum dots to FGF and bioimaging their interactions with FGFRAbstracts of Papers, 255th ACS National Meeting and Exposition, New Orleans, LA, United States, March 18-22, 2018Abstract2018Find It
FRET based assays to study the binding of fibroblast growth factor to its receptorAbstracts of Papers, 255th ACS National Meeting and Exposition, New Orleans, LA, United States, March 18-22, 2018Abstract2018Find It
Probing the role of proline-135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factorArchives of Biochemistry and BiophysicsJournal Article2018Find It
Peanut Hairy Roots: A Bioproduction Platform for Elucidating the Biosynthesis of Prenylated StilbenoidsIn Vitro Cellular and Developmental Biology-PlantAbstract2018Find It
Stilbenoid prenyltransferases define key steps in the diversification of peanut phytoalexinsJournal of Biological ChemistryJournal Article2018Find It
Backbone and side-chain H-1, N-15, and C-13 resonance assignments of a novel Staphylococcal inhibitor of myeloperoxidaseBiomolecular NMR AssignmentsJournal Article2017Find It
Modulation of Interleukin-12 activity in the presence of heparinScientific ReportsJournal Article2017Find It
Peptides with antifungal activity and methods of using the peptidesUS9556226Patent2017Find It
Heparin affinity tag and applications thereofUS9676816Patent2017Find It
Folding of Fibroblast Growth Factor 1 Is Critical for Its Nonclassical ReleaseBiochemistryJournal Article2016Find It
Acquisition of Multidimensional NMR Data on GST-Fused ProteinsBiophysical JournalAbstract2016Find It
Domain Organization in the 54-kDa Subunit of the Chloroplast Signal Recognition ParticleBiophysical JournalJournal Article2016Find It
Engineering the Structure of Human Acidic Fibroblast Growth Factor through Site Directed Mutagenesis for Increased Protein StabilityBiophysical JournalAbstract2016Find It
Production of an anti-Candida peptide via fed batch and ion exchange chromatographyBiotechnology ProgressJournal Article2016Find It
Novel Molecular Interactions of Acylcarnitines and Fatty Acids with MyoglobinJournal of Biological ChemistryJournal Article2016Find It
Protein-rich beverage developed using non-GM soybean (R08-4004) and evaluated for sensory acceptance and shelf-lifeJournal of Food Science and Technology (Mysore)Journal Article2016Find It
Physicochemical Properties and ACE-I Inhibitory Activity of Protein Hydrolysates from a Non-Genetically Modified Soy CultivarJournal of the American Oil Chemists SocietyJournal Article2016Find It
Heparin-binding peptide as a novel affinity tag for purification of recombinant proteinsProtein Expression and PurificationJournal Article2016Find It
On the role of C-Terminal tail helical domain of anabaena sensory rhodopsin transducer in unusual high stability, ligand and receptor interactionProtein ScienceConference Proceedings2016Find It
Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitorSmall GTPasesJournal Article2016Find It
Promoting binding of protein-targeting substrates by regulating interdomain dynamics within a signal recognition particle: Implications for biotechnologyAbstracts of Papers, 249th ACS National Meeting and Exposition, Denver, CO, United States, March 22-26, 2015Abstract2015Find It
Can native enzyme conformation act as a template for refolding of RNase AAbstracts, 67th Southeast/71st Southwest Joint Regional Meeting of the American Chemical Society, Memphis, TN, United States, November 4-7Abstract2015Find It
Modulating the mitogenic activity of the fibroblast growth factorAbstracts, 67th Southeast/71st Southwest Joint Regional Meeting of the American Chemical Society, Memphis, TN, United States, November 4-7Abstract2015Find It
Controlling chitosan-based encapsulation for protein and vaccine delivery (vol 35, pg 4382, 2014)BiomaterialsJournal Article2015Find It
Role of Structural Flexibility of cpSRP43 in Binding Substrates during Post-Translational TargetingBiophysical JournalAbstract2015Find It
Oxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agentsCell Death and DiseaseJournal Article2015Find It
Refolding of Denatured-Reduced Lysozyme in the Presence of Native TemplatesFASEB JournalJournal Article2015Find It
The Versatility of Isothermal Titration Calorimetry in Modern BiologyJournal of Analytical and Bioanalytical TechniquesJournal Article2015Find It
Regulation of Structural Dynamics within a Signal Recognition Particle Promotes Binding of Protein Targeting SubstratesJournal of Biological ChemistryJournal Article2015Find It
Linear starch and hexanoic acid complexation evaluated by isothermal titration calorimetryStarch-StarkeJournal Article2015Find It
Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factorBiochimica et Biophysica Acta-Proteins and ProteomicsJournal Article2014Find It
Controlling chitosan-based encapsulation for protein and vaccine deliveryBiomaterialsJournal Article2014Find It
Influence of a Central Tryptophan and of Cholesterol on the Properties of Defined Transmembrane Helical PeptidesBiophysical JournalAbstract2014Find It
Is Refolding of Lysozyme Template-DrivenBiophysical JournalAbstract2014Find It
Three-Dimensional Structure of the 54-Kda Subunit of the Chloroplast Signal Recognition Particle using Molecular ModelingBiophysical JournalAbstract2014Find It
Understanding the Structural Determinants for the Stability of Human Fibroblast Growth FactorBiophysical JournalAbstract2014Find It
Understanding the Structural Determinants of the Extreme Thermal Stability of RubredoxinBiophysical JournalAbstract2014Find It
Identification of antagonists to the vasotocin receptor sub-type 4 (VT4R) involved in stress by molecular modelling and verification using anterior pituitary cellsJournal of Biomolecular Structure and DynamicsJournal Article2014Find It
Efficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tagProtein Expression and PurificationJournal Article2014Find It
Three-dimensional Structure of the 54 kDa Subunit of the Chloroplast Signal Recognition Particle using Molecular ModelingProtein ScienceConference Proceedings2014Find It
Identification of Consensus Glycosaminoglycan Binding Strings in Proteins4th International Conference on Information Science and Applications, Pattaya, Thailand, June 24-26, 2013Conference Proceedings2013Find It
C-Terminal M4 Peptide Fragment of Albino 3 Interaction with cpSRP-43Biophysical JournalAbstract2013Find It
Investigation of the Structural Stability of cpSRP43 Chromodomain2 by Hydrogen-Deuterium ExchangeBiophysical JournalAbstract2013Find It
Membrane Permeability Induced by Stereo and Retro Analogs of Histatin 5Biophysical JournalAbstract2013Find It
Using Homo-Polypeptides to Study Charge-Charge Interactions in BiomoleculesBiophysical JournalAbstract2013Find It
Protein-Phospholipid Interactions in Nonclassical Protein Secretion: Problem and Methods of StudyInternational Journal of Molecular SciencesJournal Article2013Find It
In-Cell NMR Spectroscopy- Monitoring of the Structure, Dynamics, Folding, and Interactions of Proteins at Atomic ResolutionJournal of Analytical and Bioanalytical TechniquesJournal Article2013Find It
Molecular basis for the Kallmann syndrome-linked fibroblast growth factor receptor mutationBiochemical and Biophysical Research CommunicationsJournal Article2012Find It
Mapping the Inositol Hexakisphosphate Binding Sites on the Human Fibroblast Growth FactorBiophysical JournalAbstract2012Find It
Phosphatidylserine externalization and membrane blebbing are involved in the nonclassical export of FGF1Journal of Cellular BiochemistryJournal Article2012Find It
Characterization of a Thermostable Quadruple Mutant of Human Fibroblast Growth Factor-1Protein ScienceConference Proceedings2012Find It
Characterization of the FGF Receptor Mutations Involved in DiseaseProtein ScienceConference Proceedings2012Find It
Characterization of the Structure of the C-terminal Domain of Alb3Protein ScienceConference Proceedings2012Find It
Characterization of W-WAP and Overexpression of full length human Anosmin in Pichia pastorisProtein ScienceConference Proceedings2012Find It
Purification and Characterization of a Novel Affinity TagProtein ScienceConference Proceedings2012Find It
The Role of Heparin in Acidic Fibroblast Growth Factor SignalingProtein ScienceConference Proceedings2012Find It
Thermodynamic Characterization of a Destabilized Mutant of the Human Acidic Fibroblast Growth FactorProtein ScienceConference Proceedings2012Find It
Understanding the Binding Interactions of the 43kDa subunit of cpSRP with the C-terminal Domain of Alb3Protein ScienceConference Proceedings2012Find It
Purification and Characterization of Recombinant L23Biophysical JournalAbstract2011Find It
The Structural and Functional Role Fo the Sole Tryptophan Residue in the Human Acidic Fibroblast Growth FactorBiophysical JournalAbstract2011Find It
NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1)Biochimica et Biophysica Acta-BiomembranesJournal Article2010Find It
Investigation of W121 on the Conformation and Functional Properties of the Human Acidic Fibroblast Growth Factor-1Biophysical JournalAbstract2010Find It
A Dynamic cpSRP43-Albino3 Interaction Mediates Translocase Regulation of Chloroplast Signal Recognition Particle (cpSRP)-targeting ComponentsJournal of Biological ChemistryJournal Article2010Find It
Protein Targeting to the Albino3 InsertaseFASEB JournalJournal Article2010Find It
Understanding the Role of Ankyrin Domain of the 43-Kda Subunit of the Chloroplast Signal Recognition Particle in Protein TargetingBiophysical JournalAbstract2010Find It
Understanding the Effects of Molecular Crowding on the Structure and Stability of Proteins Using NMR SpectroscopyBiophysical JournalAbstract2010Find It
The Monomerization of a Dimeric, Calcium-Binding Protein Involved in the Non-Classical Export of Fibroblast Growth Factor 1Biophysical JournalAbstract2010Find It
Rational Design of Acidic Human Fibroblast Growth Factor (hFGF-1) with Increased Stability and Mitogenic ActivityBiophysical JournalAbstract2010Find It
Design of Novel Methods to Eliminate DNA Binding to Recombinant ProteinsBiophysical JournalAbstract2010Find It
3D Solution Structure of the C-terminal Chromodomain of the Chloroplast Signal Recognition ParticleBiophysical JournalAbstract2010Find It
Design of Novel Affinity Tags to Increase Recovery of Recombinant Proteins in Ther Soluble FormsBiophysical JournalAbstract2010Find It
Defining the Interaction Between S100A13 and Annexin II Peptide: Insight into Non-Classical SecretionBiophysical JournalAbstract2010Find It
Characterization of the Minimalistic Fgf-D2 Domain InterfaceBiophysical JournalAbstract2010Find It
Cation-Pi Interactions Contribute Significantly to the Stability of FGF and the FGFRBiophysical JournalAbstract2010Find It
Binding of Antimicrobial Lactoferricin Peptides to Targets in the Angiogenesis PathwayBiophysical JournalAbstract2010Find It
A Biophysical Investigation of the Non-Classical Release Complex of Fibroblast Growth Factor-1Biophysical JournalAbstract2010Find It
Response to Falk and Sinning: The C Terminus of Alb3 Interacts with the Chromodomains 2 and 3 of cpSRP43Journal of Biological ChemistryJournal Article2010Find It
Protein folding does not prevent the nonclassical export of FGF1 and S100A13Biochemical and Biophysical Research CommunicationsJournal Article2009Find It
Biophysical Characterization of FGF Signaling ComplexBiophysical JournalAbstract2009Find It
Cation-pi Interactions Contribute Significantly To The Stability Of The D2 Domain Of Fibroblast Growth Factor ReceptorBiophysical JournalAbstract2009Find It
Designing Fibroblast Growth Factor with Higher Heparin Binding AffinityBiophysical JournalAbstract2009Find It
Effect of Osmolytes on Protein Stability and FoldingBiophysical JournalAbstract2009Find It
Interactions Defined between S100A13 and Annexin Peptides: Insight into Non-Classical SecrectionBiophysical JournalAbstract2009Find It
Specificity Of The Helical Conformation Induced By 2, 2, 2, TrifluoroethanolBiophysical JournalAbstract2009Find It
Structural and Functional Role of Proline Residues in Fibroblast Growth Factor-1Biophysical JournalAbstract2009Find It
Understanding the Mechanism of Autoregulation of FGF SignalingBiophysical JournalAbstract2009Find It
Understanding the Mechanism of the Anti-angiogenic Activity of SuraminBiophysical JournalAbstract2009Find It
The Membrane-binding Motif of the Chloroplast Signal Recognition Particle Receptor (cpFtsY) Regulates GTPase ActivityJournal of Biological ChemistryJournal Article2009Find It
A superior drug carrier - aponeocarzinostatin in partially unfolded state fully protects the labile antitumor enediyneJournal of Biomedical ScienceJournal Article2009Find It
Trichloroacetic acid-induced protein precipitation involves the reversible association of a stable partially structured intermediateProtein ScienceJournal Article2009Find It
Structural analysis of a novel hFGFR2D2 dimer: Insights into the FGF signaling pathwayAbstracts of Papers, 236th ACS National Meeting, Philadelphia, PA, United States, August 17-21, 2008Abstract2008Find It
Effect of Osmolytes on Protein Stability and FoldingAbstracts, 64th Southwest Regional Meeting of the American Chemical Society, Little Rock, AR, United States, October 1-4Abstract2008Find It
A method for the prevention of thrombin-induced degradation of recombinant proteinsAnalytical BiochemistryJournal Article2008Find It
Is association of labile enediyne chromophore a mutually assured protection for carrier protein?Analytical BiochemistryJournal Article2008Find It
H-1, C-13 and N-15 resonance assignments of the C-terminal domain of the 43 kDa subunit of the chloroplast signal recognition particleBiomolecular NMR AssignmentsJournal Article2008Find It
A light scattering study of the interaction of fibroblast growth factor (FGF) with its receptorBiophysical JournalJournal Article2008Find It
Secretion without GolgiJournal of Cellular BiochemistryJournal Article2008Find It
Assembly of chloroplast signal recognition particle involves structural rearrangement in cpSRP43Journal of Molecular BiologyJournal Article2008Find It
Matrix metalloproteinase in avian bile fluidPoultry ScienceJournal Article2008Find It
A new dimeric structure of FGFR D2 domain may contribute to the FGF signaling pathwayAbstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007Abstract2007Find It
Molecular cloning, overexpression and characterization of human interleukin 1 alphaBiochemical and Biophysical Research CommunicationsJournal Article2007Find It
Relevance of partially structured states in the non-classical secretion of acidic fibroblast growth factorBiochemistryJournal Article2007Find It
S100A13-lipid interactions - role in the non-classical release of the acidic fibroblast growth factorBiochimica et Biophysica Acta-BiomembranesJournal Article2007Find It
Characterization of residual structure(s) in the disordered state(s) of fibroblast growth factorBiophysical JournalAbstract2007Find It
Investigation of the mechanism underlying the anti-mitogenic activity of suraminBiophysical JournalAbstract2007Find It
Is heparin binding a prerequisite for FGF signaling?Biophysical JournalAbstract2007Find It
Understanding the role of divalent cations in FGF signalingBiophysical JournalAbstract2007Find It
Carbon nanotubes prevent 2,2,2 trifluoroethanol induced aggregation of proteinCarbonJournal Article2007Find It
Structures of pahayokolides A and B, cyclic peptides from a Lyngbya spJournal of Natural ProductsJournal Article2007Find It
Refolding of a small all beta-sheet protein proceeds with accumulation of kinetic intermediatesArchives of Biochemistry and BiophysicsJournal Article2006Find It
Release of FGF1 and p40 synaptotagmin 1 correlates with their membrane destabilizing abilityBiochemical and Biophysical Research CommunicationsJournal Article2006Find It
Understanding the mechanism of the antimitogenic activity of suraminBiochemistryJournal Article2006Find It
Cold instability of aponeocarzinostatin and its stabilization by labile chromophore. Erratum to document cited in CA143:148568]Biophysical JournalJournal Article2006Find It
Copper binding affinity of S100A13, a key component of the FGF-1 nonclassical copper-dependent release complexBiophysical JournalJournal Article2006Find It
Three-Dimensional Solution Structure of a Unique S100 ProteinAbstracts, 57th Southeast/61st Southwest Joint Regional Meeting of the American Chemical Society, Memphis, TN, United States, November 1-4Abstract2005Find It
Equilibrium unfolding of an oligomeric protein involves formation of a multimeric intermediate state(s)Biochemical and Biophysical Research CommunicationsJournal Article2005Find It
Three-dimensional solution structure of a unique S100 proteinBiochemical and Biophysical Research CommunicationsJournal Article2005Find It
Molecular mechanism of inhibition of nonclassical FGF-1 exportBiochemistryJournal Article2005Find It
Solution structure of the ligand binding domain of the fibroblast growth factor receptor: Role of heparin in the activation of the receptorBiochemistryJournal Article2005Find It
The C2A domain of synaptotagmin exhibits a high binding affinity for copper: Implications in the formation of the multiprotein FGF release complexBiochemistryJournal Article2005Find It
Cold instability of aponeocarzinostatin and its stabilization by labile chromophoreBiophysical JournalJournal Article2005Find It
Three-dimensional solution structures of the chromodomains of cpSRP43Journal of Biological ChemistryJournal Article2005Find It
Time-dependent changes in the denatured state(s) influence the folding mechanism of an all beta-sheet proteinJournal of Biological ChemistryJournal Article2005Find It
Resonance assignments for mouse S100A13Journal of Biomolecular NMRJournal Article2005Find It
Monitoring protein folding at atomic resolutionAccounts of Chemical ResearchJournal Article2004Find It
Cloning, overexpression, and characterization of cobrotoxinBiochemical and Biophysical Research CommunicationsJournal Article2004Find It
Molecular cloning, overexpression, and characterization of the ligand-binding D2 domain of fibroblast growth factor receptorBiochemical and Biophysical Research CommunicationsJournal Article2004Find It
Characterization of molten globule state with novel drug delivery features in anti-tumor drug neocarzinostatinBiophysical JournalAbstract2004Find It
Letter to the Editor: H-1, C-13 and N-15 chemical shift assignments of the D2 domain of the fibroblast growth factor receptorJournal of Biomolecular NMRJournal Article2004Find It
Structurally homologous all beta-barrel proteins adopt different mechanisms of foldingBiophysical JournalJournal Article2003Find It